Profile: Cağhan KIZIL





 Ca?han KIZIL, PhD

German Center for Neurodegenerative Diseases (DZNE) Dresden, Helmholtz Association,
DFG-Research Center for Regenerative Therapies
Dresden, Cluster of Excellence at the TU Dresden (CRTD)
Fetscherstraße 105, 01307 Dresden, Germany




Phone: +49 (351) 458 82315
Email: caghan.kizil@dzne.de caghan.kizil@crt-dresden.de
Web: http://www.crt-dresden.de/research/crtd-core-groups/kizil.html
Fields of Expertise:
  • zebrafish
  • regeneration
  • neural stem cells
  • neurodegeneration
Vita:
Caghan Kizil got his BSc degree in Middle East Technical University, Ankara Turkey. He received his MSc degree from International Max Planck Research School for Molecular Biology and University of Gottingen. He obtained his PhD from Max Planck Institute for Developmental Biology, Tübingen, working on the injury-induced molecular pathways in caudal fin regeneration of zebrafish in Christiane Nüsslein-Volhard’s lab. He moved to Dresden for his post-doctoral work in DFG-Center for Regenerative Therapies Dresden (CRTD), at the TU Dresden in Michael Brand’s lab. He started working on adult zebrafish brain and radial glial cells and the work led to identification of particular molecular programs initiating and maintaining the special regenerative capacity of the neural progenitor cells of the adult zebrafish brain upon acute injuries. Since January 2014, he has a joint appointment in DZNE Dresden and CRTD as a Helmholtz Young Investigator research group leader. Kizil’s lab is interested in investigating the molecular mechanisms underlying the regenerative ability of the zebrafish brain upon various stimulations. The main motivation for his research group at DZNE in Dresden is to understand what it takes in terms of molecular programs for zebrafish brain to regenerate itself after neurodegeneration, and which parts of those relevant molecular programs are missing in mammalian brains. He received several prizes and awards including Helmholtz Young Investigator award, Alzheimer Research Initiative research award, Turkish Ministry of Education distinction prize; and fellowships from International Society for Stem Cell Research (ISSCR), National Institutes of Health (NIH), The Company of Biologists, Keystone Symposia, Gordon Research Conferences, Technische Universitaet Dresden, Max Planck Society and TUBITAK.
Selected Publications:
  • Kizil C, Kyritsis N, Dudczig S, Kroehne V, Freudenreich D, Kaslin J, Brand M. Regenerative neurogenesis from neural progenitor cells requires injury-induced expression of Gata3. Dev Cell 2012;23(6):1230-7.
  • Kyritsis N, Kizil C, Zocher S, Kroehne V, Kaslin J, Freudenreich D, Iltzsche A, Brand M. Acute inflammation initiates the regenerative response in the adult zebrafish brain. Science 2012;338(6112):1353-6.
  • Kizil C, Kaslin J, Kroehne V, Brand M. Adult neurogenesis and brain regeneration in zebrafish. Dev Neurobiol 2012;72(3):429-61.
  • Kizil C, Dudczig S, Kyritsis N, Machate A, Blaesche J, Kroehne V, Brand M. The chemokine receptor cxcr5 regulates the regenerative neurogenesis response in the adult zebrafish brain. Neural Dev 2012;7:27.
  • Kizil C, Brand M. Cerebroventricular microinjection (CVMI) into adult zebrafish brain is an efficient misexpression method for forebrain ventricular cells. PLoS One 2011;6(11):e27395.
  • Kyritsis N*, Kizil C*, Brand M. Neuroinflammation and central nervous system regeneration in vertebrates. Trends in Cell Biology 2014. 24(2):128-35





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